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Vatalanib hydrochloride

CAS No. 212141-52-1

Vatalanib hydrochloride( —— )

Catalog No. M37594 CAS No. 212141-52-1

Vatalanib hydrochloride (PTK787; ZK-222584; CGP-797870) functions as an inhibitor of VEGFR2/KDR, displaying an IC50 value of 37 nM .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Vatalanib hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Vatalanib hydrochloride (PTK787; ZK-222584; CGP-797870) functions as an inhibitor of VEGFR2/KDR, displaying an IC50 value of 37 nM .
  • Description
    Vatalanib (PTK787; ZK-222584; CGP-797870) hydrochloride is an inhibitor of VEGFR2/KDR with an IC50 of 37 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    212141-52-1
  • Formula Weight
    383.27
  • Molecular Formula
    C20H16Cl2N4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C=1C2=C(C(CC=3C=CN=CC3)=NN1)C=CC=C2)C4=CC=C(Cl)C=C4.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wood JM, et al. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res. 2000;60(8):2178-2189.?
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