Vatalanib hydrochloride( —— )

Catalog No. M37594 CAS No. 212141-52-1

Vatalanib hydrochloride (PTK787; ZK-222584; CGP-797870) functions as an inhibitor of VEGFR2/KDR, displaying an IC50 value of 37 nM .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Vatalanib hydrochloride
Note

Research use only, not for human use.
Brief Description

Vatalanib hydrochloride (PTK787; ZK-222584; CGP-797870) functions as an inhibitor of VEGFR2/KDR, displaying an IC50 value of 37 nM .
Description

Vatalanib (PTK787; ZK-222584; CGP-797870) hydrochloride is an inhibitor of VEGFR2/KDR with an IC50 of 37 nM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

212141-52-1
Formula Weight

383.27
Molecular Formula

C20H16Cl2N4
Purity

>98% (HPLC)
Solubility

——
SMILES

N(C=1C2=C(C(CC=3C=CN=CC3)=NN1)C=CC=C2)C4=CC=C(Cl)C=C4.Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Wood JM, et al. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res. 2000;60(8):2178-2189.?

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